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Recombinant Human KGF
名稱 Recombinant Human KGF
型號
更新時(shí)間 2023-09-24
特點(diǎn) FGF-7是已知的FGF家族的成員。這個(gè)家庭中發(fā)揮核心作用的蛋白質(zhì)在產(chǎn)前發(fā)展和產(chǎn)后的生長和再生各種組織,通過促進(jìn)細(xì)胞增殖和分化。FGF-7是一個(gè)特定的上皮細(xì)胞和角化細(xì)胞分裂素因素。 FGF-7信號通過FGFR 2 b。FGF-7腎和肺發(fā)展中所起的作用,血管再生和傷口愈合。FGF-7 18.9 kDa蛋白由163個(gè)氨基酸殘基組成。使用所有無動物生產(chǎn)試劑。}
  • 詳細(xì)內(nèi)容

一.產(chǎn)品名稱:Recombinant Human KGF

二.Catalog Number:AF-100-19

三.Synonyms:Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7

四.Description:

KGF/FGF-7 is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. KGF/FGF-7 is a mitogen factor specific for epithelial cells and keratinocytes. KGF/FGF-7 signals through FGFR 2b. KGF/FGF-7 plays a role in kidney and lung development, angiogenesis, and wound healing. Recombinant human KGF/FGF-7 is a 18.9 kDa protein consisting of 163 amino acid residues. Manufactured using all non-animal reagents.

五.AA Sequence:

CNDMTPEQMA TNVNCSSPER HTRSYDYMEG GDIRVRRLFC RTQWYLRIDK RGKVKGTQEM KNNYNIMEIR TVAVGIVAIK GVESEFYLAM NKEGKLYAKK ECNEDCNFKE LILENHYNTY ASAKWTHNGG EMFVALNQKG IPVRGKKTKK EQKTAHFLPM AIT

六.Source:E.coli

七.Purity:Greater than 95% by SDS-PAGE gel and HPLC analyses.

八.Biological Activity:

The ED50 as determined by the dose-dependent stimulation of thymidine uptake by KGF-responsive BaF3 cells is ≤ 10 ng/ml corresponding to a specific activity of ≥ 1 x 105 units/mg.

九.Cross Reactivity:Human, Rat, Mouse

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