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Recombinant Murine GM-CSF
名稱 Recombinant Murine GM-CSF
型號(hào)
更新時(shí)間 2023-09-24
特點(diǎn) gm - csf的造血生長(zhǎng)因子刺激中性粒細(xì)胞和巨噬細(xì)胞的發(fā)展和促進(jìn)早期的擴(kuò)散和發(fā)展紅色的巨核細(xì)胞和嗜酸性粒細(xì)胞的祖細(xì)胞。生產(chǎn)的內(nèi)皮細(xì)胞,單核細(xì)胞、成纖維細(xì)胞和淋巴細(xì)胞。gm - csf抑制中性粒細(xì)胞遷移和增強(qiáng)的功能活動(dòng)end-cells成熟。人類和小鼠分子具有種特異性,表現(xiàn)出沒(méi)有跨物種反應(yīng)性。}
  • 詳細(xì)內(nèi)容

一.產(chǎn)品名稱:Recombinant Murine GM-CSF

二.Catalog Number:AF-315-03

三.Synonyms:Granulocyte/Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-α

四.Description:

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant murine GM-CSF is a 14.2 kDa globular protein consisting of 125 amino acid residues. Manufactured using all non-animal reagents.

五.AA Sequence:

MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK

六.Source:E.coli

七.Purity:Greater than 98% by SDS-PAGE gel and HPLC analyses.

八.Biological Activity:

The ED50 was determined by the dose-dependent stimulation of the proliferation of murine FDC-P1 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.

九.Cross Reactivity:

Rat, Mouse, Trout, N/A, Human

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